Coronavirus

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Everpack
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Wayland said:

Everpack said:

Daviewolf83 said:

Everpack said:

Regarding your point 9, what is the justification for requiring young and healthy athletes to be boosted? Why, beyond doing something for the sake of doing something, should that demographic be required to take a booster?
As I said, all students at Wake have to be boosted prior to next semester and they were told to try and get boosted while they were home this past week. My son got his booster last week and had 36 hours of chills and headaches. Same reaction he had when he got vaccinated last March.

I just saw on Twitter that Duke will also require boosters for all students before arriving for the Spring semester. I expect other schools to do the same, but likely not the public universities in NC. I do expect VT and Virginia to require it, since they required vaccinations for this past Fall semester.


Sorry, I wasn't clear in my question. I want to hear your opinion on requiring young, healthy athletes to get the booster shot. What is the justification of the requirement/mandate?

Public health and academics run amok.

There is absolutely no justification to boosting healthy young people but no one will stand up to public health.

Boosters should have been used judiciously in severely at-risk populations and that is it.

I am disgusted at our policy makers,, institutions, and public health for continuing forward without any critical thought.

They have allowed fear to dominate reason and have basically become a cult to a fictitious "The Science" and have been completely unable to update their priors at any point in the last two years.

They need to get the **** out of whatever bubble or feedback loop they are stuck in.




Tell me something I don't know. My wife has/had an old friend that took this **** hook, line and sinker. Late 30's, no health issues and lives in a rural part of WNC. She wouldn't leave the house. Shamed anyone for daring not don a mask. When kids went back to in person school in August 2020, she opted out and kept her kids at home. She pushed grandma out of the way to get her doses of the vaccine and booster. Then, to take the cake, quite literally I might add, she proudly posted pictures on social media of a COVID vaccine cake she had made for her children after their second shots.

You're not going to fix her or those like her. This is their religion.
Mormad
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I think both sides are staying pretty rigidly religious about this? At least that is what I've witnessed on the clinal side.
packgrad
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Quite a big difference in religion when one is trying to impose their religion on to you.

Everpack
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Mormad said:

I think both sides are staying pretty rigidly religious about this? At least that is what I've witnessed on the clinal side.


If wanting to live life is being "rigidly religious," guilty as charged. Maybe I should make a cake to announce it.
bgr3
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packgrad said:

Quite a big difference in religion when one is trying to impose their religion on to you.
An important asymmetry, for sure. Anyone who wants to mask/test/boost themselves is more than welcome to until the end of time.

One of my favorite (and simultaniously infuriating) things about reading the coverage of the Omicron variant and the seasonal wave in the northeast is to watch people who have convinced themselves that the seasonal waves in the south were due to stupid rubes in red states not following The Science (TM). They really thought their arbitrary policies and mandates would actually completely stop a highly infectious airborne virus from spreading despite there being no place in the world that has been able to accomplish that, no matter how draconian the measures have been.

The messaging shift we're starting to see is a tacit acknowledgment of something many of us knew over a year ago: politicians can't save you from catching a highly infectious virus and it is not a moral failing of an individual to catch said virus. It sure is fun though watching people who have spent the last year plus treating it as such find these things out the hard way, although I know I should rise above that lol.
Wayland
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New Cooper briefing today.

Telling everyone to 'Get Boosted'.

Mandy putting out the Omicron fear porn.... the SUPER MOST contagious COVID ever.
Oldsouljer
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TheStorm said:

Daviewolf83 said:

Wayland said:

Werewolf said:




Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

(https://t.me/LeakyVax/904)Original Antigenic Sin: prior common colds with coronaviruses were supposed to have some protective "back-boost" effect for COVID. This turns out to be just the opposite. In this study it was observed that those who had a high baseline of betacoronavirus antibodies from non-SARS-CoV-2 infections took longer to clear the virus from their system than those with a lower betacoronavirus antibody baseline.

This demonstrates that cross-reactive antibodies that are sub- or non-neutralizing can increase disease severity. This has negative implications for COVID vaccinees as variants continue to evolve away from the immunity they have been imprinted with.

(This finding is of course being used to justify development of a "pan-coronavirus" vaccine that covers all variants, rather than pausing and reassessing the current strategy.)



Something like OAS has been one of my fears this whole time. Just feel like due diligence is lacking.
My concern regarding repeated boosting, particularly by a mRNA based vaccine is the increased chance of autoimmune disorders. Having a daughter that suffers with an autoimmune disease that hit her in her early twenties, gives me great pause. It is for this reason that I have decided to wait for the Novavax vaccine and not boost with an mRNA based vaccine. I believe there needs to be a lot more research and studies regarding repeated boosting by mRNA vaccines, before boosters are recommended.

I got vaccinated in late April and I believe I am protected from severe illness by T and B-Cells. If I have a breakthrough case (something I consider likely, given Omicron transmissibility), I will utilize some of the latest treatments for Covid-19. This is not 2020, where we had no vaccine and limited treatment options. To treat us like it is still 2020 is mistake and undermines the credibility (what little bit they have left) of the people making healthcare policy. There is too much focus on waning antibodies in the press and by policy makers and not enough emphasis of another key component of our immune system.

Today, The Elf said we have to be vaccinated AND wear a mask, it is not an either/or proposition. He and the other health policy advisors can not make up their minds what works and continue to move the goal posts. Last Spring, the message was get vaccinated and you do not need to mask. After Delta hit, the message became "mask up, since vaccinated people can transmit the virus, so we need to protect others." Now it is vaccines are not very good at keeping you from becoming infected, so you have to wear a mask for an extra level of protection. This is in addition to being boosted. The Elf also said he does not foresee a day when masks will not be required on airplanes. Thank goodness I can drive to all of my son's games next season (yes - he is returning for a sixth season of college football, at the invitation of his head coach).

If my company requires boosting before the Novavax vaccine is approved and available (currently requires full vaccination to stay employed with the company), I will move up my planned retirement this year. I can retire any day I want to, but had planned to work for several more months. I am currently responsible for a large, multimillion dollar project that spans multiple countries and it will not end for another year, but will walk away from it all if necessary.
This is exactly where I am. I am not taking another mRNA based vaccine… period. I've had some really weird sensations that I've never had before, since I got those shots. Still going to ask my primary about them (my appointment got pushed from just after Thanksgiving to just after Christmas) here shortly when I go to see him.
Are one of those sensations an occasional "fluttering" in the chest? That's bothered me this year, never noticed it before 2021, and got the jab in April. I did bring it up with my primary but we couldn't rule out another problem for which I've been taking a lot of Tums, also this year. I'm scheduled for a gastro probe next month to see if there's an esophageal problem. Primary didn't seem to concerned about my heart and didn't have any problem with me doing extreme cardio workouts at my age.
packgrad
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Oldsouljer said:

TheStorm said:

Daviewolf83 said:

Wayland said:

Werewolf said:




Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

(https://t.me/LeakyVax/904)Original Antigenic Sin: prior common colds with coronaviruses were supposed to have some protective "back-boost" effect for COVID. This turns out to be just the opposite. In this study it was observed that those who had a high baseline of betacoronavirus antibodies from non-SARS-CoV-2 infections took longer to clear the virus from their system than those with a lower betacoronavirus antibody baseline.

This demonstrates that cross-reactive antibodies that are sub- or non-neutralizing can increase disease severity. This has negative implications for COVID vaccinees as variants continue to evolve away from the immunity they have been imprinted with.

(This finding is of course being used to justify development of a "pan-coronavirus" vaccine that covers all variants, rather than pausing and reassessing the current strategy.)



Something like OAS has been one of my fears this whole time. Just feel like due diligence is lacking.
My concern regarding repeated boosting, particularly by a mRNA based vaccine is the increased chance of autoimmune disorders. Having a daughter that suffers with an autoimmune disease that hit her in her early twenties, gives me great pause. It is for this reason that I have decided to wait for the Novavax vaccine and not boost with an mRNA based vaccine. I believe there needs to be a lot more research and studies regarding repeated boosting by mRNA vaccines, before boosters are recommended.

I got vaccinated in late April and I believe I am protected from severe illness by T and B-Cells. If I have a breakthrough case (something I consider likely, given Omicron transmissibility), I will utilize some of the latest treatments for Covid-19. This is not 2020, where we had no vaccine and limited treatment options. To treat us like it is still 2020 is mistake and undermines the credibility (what little bit they have left) of the people making healthcare policy. There is too much focus on waning antibodies in the press and by policy makers and not enough emphasis of another key component of our immune system.

Today, The Elf said we have to be vaccinated AND wear a mask, it is not an either/or proposition. He and the other health policy advisors can not make up their minds what works and continue to move the goal posts. Last Spring, the message was get vaccinated and you do not need to mask. After Delta hit, the message became "mask up, since vaccinated people can transmit the virus, so we need to protect others." Now it is vaccines are not very good at keeping you from becoming infected, so you have to wear a mask for an extra level of protection. This is in addition to being boosted. The Elf also said he does not foresee a day when masks will not be required on airplanes. Thank goodness I can drive to all of my son's games next season (yes - he is returning for a sixth season of college football, at the invitation of his head coach).

If my company requires boosting before the Novavax vaccine is approved and available (currently requires full vaccination to stay employed with the company), I will move up my planned retirement this year. I can retire any day I want to, but had planned to work for several more months. I am currently responsible for a large, multimillion dollar project that spans multiple countries and it will not end for another year, but will walk away from it all if necessary.
This is exactly where I am. I am not taking another mRNA based vaccine… period. I've had some really weird sensations that I've never had before, since I got those shots. Still going to ask my primary about them (my appointment got pushed from just after Thanksgiving to just after Christmas) here shortly when I go to see him.
Are one of those sensations an occasional "fluttering" in the chest? That's bothered me this year, never noticed it before 2021, and got the jab in April. I did bring it up with my primary but we couldn't rule out another problem for which I've been taking a lot of Tums, also this year. I'm scheduled for a gastro probe next month to see if there's an esophageal problem. Primary didn't seem to concerned about my heart and didn't have any problem with me doing extreme cardio workouts at my age.
I've periodically had that as well, after my 2 bouts of AFIB after my second dose. Not even considering the booster. I don't go back to my primary until March, so I'll wait until then for his evaluation.
TheStorm
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Yes, that's exactly what it is. Nothing painful, sometimes also manifests itself as a "slightly pulled muscle" during a benign body movement… also have sporadically felt the "pulled muscle" sensation up the back of my neck (left side only) into my head when making a basic movement in the car, checking blind spots, etc.

Weird. and something that never happened until the last four (4) months.
statefan91
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Mormad
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packgrad said:

Quite a big difference in religion when one is trying to impose their religion on to you.


Politically, sure. But I'm not really talking about politics. I leave that to you guys. I'm talking about average joes on each side of these constant covid debates. I'm not sure the wife's ex friend can impose her religion on anybody except her family, even though she may want to.
Mormad
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I don't guess it's any of my business, but have you been seen by a cardiologist yet?
packgrad
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Yes. Went during my second bout, when I stayed in AFIB for several days. Put me on blood thinners for a month, then took me off and gave me the all clear. I had done a cardiac stress test at the beginning of the year just a couple months before and everything was good.
Mormad
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Great to hear, man. That's awesome.
Wayland
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Mormad said:

packgrad said:

Quite a big difference in religion when one is trying to impose their religion on to you.


Politically, sure. But I'm not really talking about politics. I leave that to you guys. I'm talking about average joes on each side of these constant covid debates. I'm not sure the wife's ex friend can impose her religion on anybody except her family, even though she may want to.
I have typed three massive responses to this... and deleted them all.

(Mostly because they weren't directed at you and just me ranting).

But this has never been political to me.
Wayland
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If Omicron is going to take over in a few weeks, "Everybody Get Boosted *against wild type*" might not be a great message.

You are just going to massively increase vaccine hesitancy when the wild-type booster does jack-**** against Omicron, despite the flailing public health messaging and college mandates that healthy young people should be boosted.
Wayland
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Wayland said:



If Omicron is going to take over in a few weeks, "Everybody Get Boosted *against wild type*" might not be a great message.

You are just going to massively increase vaccine hesitancy when the wild-type booster does jack-**** against Omicron, despite the flailing public health messaging and college mandates that healthy young people should be boosted.
Speaking of which. Headline on WRAL this morning "6 Omicron cases in Durham"

CDC says: "Hold my beer!"



https://covid.cdc.gov/covid-data-tracker/#variant-proportions

Going to assume a little data backlog. Again only has regional level data.

Wayland
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Also, something strange going on.

HealthData.gov and NC DHHS data is diverging.

Daviewolf83
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Staff
As I posted in my lengthy post earlier today - viruses mutate in ways to become more transmittable and in ways that avoid the body's defenses. Omicron has mutated in a way we should have expected and no one should act surprised the virus is now able to avoid the antibodies produced by the vaccines and previous infection. I mentioned last week that vaccine protection has seen a 5-fold decrease with the Omicron variant.

Vaccines will protect you from severe illness, hospitalizations, and deaths. Protection from infection will be much lower than it was with Delta and other variants.
Wayland
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Good thing we didn't follow the clear data from Europe in spring 2020 that schools were fine to open in the fall 2020.

Certainly not going to be any long term consequences of keeping schools closed for over a year.




Everpack
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Wayland said:

Good thing we didn't follow the clear data from Europe in spring 2020 that schools were fine to open in the fall 2020.

Certainly not going to be any long term consequences of keeping schools closed for over a year.







What's sad is that the academic failures are the least of issues with students. Our ****ty society is full of people that have no business raising children, and without teachers and schools to do it for them over the last 20ish months, they just didn't. Kids don't know how to use scissors, can't sit in a desk for more than 32 seconds, taking dumps in the floor, and my favorite, wiping feces on bathroom walls. This generation should be well prepared to continue the death spiral of our society that their worthless parents have already accelerated us into.
Daviewolf83
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Staff
Some potential good news this morning. If the treatments work as well as expected (I am crossing my fingers), they could reduce some of the burden on hospitals, since they can be administered at home. Likely will be limited to high-risk patients at this point, since there is limited supply of the drugs. As supply increases, they could see more widespread use. I do believe Paxlovid is the more promising of the two treatments, but I hope both work as expected.

Tatted_Umpire
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Daviewolf83 said:

Some potential good news this morning. If the treatments work as well as expected (I am crossing my fingers), they could reduce some of the burden on hospitals, since they can be administered at home. Likely will be limited to high-risk patients at this point, since there is limited supply of the drugs. As supply increases, they could see more widespread use. I do believe Paxlovid is the more promising of the two treatments, but I hope both work as expected.


SARS-CoV2 infection results in an age-related acute respiratory disease spectrum that can be life-threatening, especially in the elderly and individuals with select underlying comorbidies [14]. rNHC has the potential to have therapeutic benefit in this setting. However, there are risks for the host in that the same mutagenic activity that impacts viral replication has the potential for incorporation and mutagenesis of host DNA. This risk can be inferred based on the common intermediate of the ribonucleoside diphosphate shared in the synthesis of both ribonucleoside triphosphates and 2-deoxyribonucleoside triphosphates. The concern would be that mutations in host DNA could contribute to the development of cancer, or cause birth defects either in a developing fetus or through incorporation into sperm precursor cells…

https://moderndiscontent.substack.com/p/the-possible-side-effect-of-mercks
RunsWithWolves26
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May I just say that Davie sir, you are a national treasure to this thread. As someone who has a brother in the medical field and has been pounding me about getting a booster, I'm glad I have some ammo in the gun against him on christmas. I was supposed to get my booster last Friday and decided to hold off. Will continue until other options are available.
Daviewolf83
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Staff
Below is my projected graph of daily hospital admissions, with the latest seven days of actual daily hospital admissions for Covid. As I have mentioned in the past, I track daily hospital admissions, since it is a lot less sticky than the daily number of people hospitalized and less noisy than daily cases.

As you can see, the current daily hospitalizations have been below my projections for the last few days of data. The data has some lag and NCDHHS has only provided data through 12/17. I do have some concern that the numbers could increase with the Omicron variant, but I am hopeful they will not. Reports of fewer patients being hospitalized gives me some hope the Winter wave will not be as bad as many are projecting and they remain more in line with my projection. I have not changed my overall projection, since I published it on this thread a few weeks ago.


Wayland
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Daviewolf83 said:

Below is my projected graph of daily hospital admissions, with the latest seven days of actual daily hospital admissions for Covid. As I have mentioned in the past, I track daily hospital admissions, since it is a lot less sticky than the daily number of people hospitalized and less noisy than daily cases.

As you can see, the current daily hospitalizations have been below my projections for the last few days of data. The data has some lag and NCDHHS has only provided data through 12/17. I do have some concern that the numbers could increase with the Omicron variant, but I am hopeful they will not. Reports of fewer patients being hospitalized gives me some hope the Winter wave will not be as bad as many are projecting and they remain more in line with my projection. I have not changed my overall projection, since I published it on this thread a few weeks ago.




If the numbers increase, it will likely be a lot of 'with' not 'from' if Delta gets replaced.

Maybe something like Denmark and hospitalizations still go down?


I am still baffled at the rate of replacement, (if it holds).

Not that we track final outcomes really anymore, but still waiting for deaths to react (even if only incidentally). Although death reporting was super delayed last winter.... this past summer wave not so much.



PortCityPackFan
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Just got a text that New Hanover County is going to re-visit adding back a mask mandate at a meeting in January…..insanity.
Daviewolf83
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Staff
Wayland said:

Daviewolf83 said:

Below is my projected graph of daily hospital admissions, with the latest seven days of actual daily hospital admissions for Covid. As I have mentioned in the past, I track daily hospital admissions, since it is a lot less sticky than the daily number of people hospitalized and less noisy than daily cases.

As you can see, the current daily hospitalizations have been below my projections for the last few days of data. The data has some lag and NCDHHS has only provided data through 12/17. I do have some concern that the numbers could increase with the Omicron variant, but I am hopeful they will not. Reports of fewer patients being hospitalized gives me some hope the Winter wave will not be as bad as many are projecting and they remain more in line with my projection. I have not changed my overall projection, since I published it on this thread a few weeks ago.




If the numbers increase, it will likely be a lot of 'with' not 'from' if Delta gets replaced.

Maybe something like Denmark and hospitalizations still go down?


I am still baffled at the rate of replacement, (if it holds).

Not that we track final outcomes really anymore, but still waiting for deaths to react (even if only incidentally). Although death reporting was super delayed last winter.... this past summer wave not so much.




Deaths will take some time to react to the Omicron variant. I think it will be early January before you begin to see deaths kick in. Most people in hospital now are likely Delta variant patients. I do not expect most of the patients to switch over to Omicron patients until early/mid January. It will be a mix for the next two to three weeks.
GuerrillaPack
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Does anyone know the latest on this illegal OSHA mandate by Fuhrer Biden for companies with over 100 employees to require the vaxx or testing? I've been loosely paying attention, and heard weeks ago about some Federal court decisions blocking it, and then a recent court possibly allowing it. Which court orders take precedent?
"Ye are not of the world, but I have chosen you out of the world, therefore the world hateth you." - John 15:19
82TxPackFan
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Wayland said:

New Cooper briefing today.

Telling everyone to 'Get Boosted'.

Mandy putting out the Omicron fear porn.... the SUPER MOST contagious COVID ever.

Only 10 more days until the wicked witch departs.

Ding Dong the witch is dead!!
statefan91
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Daviewolf83
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Staff
As an early Christmas present, I thought I would give everyone a new chart to ponder. The chart below shows the daily cases (by specimen date) plotted against the daily deaths (by date of death). You can see clearly that the peak in deaths always lags the peak in cases and this makes sense. What you will also notice is the recent increase in cases is not being met with an increase in deaths, as it did in past waves.

Oldsouljer
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PortCityPackFan said:

Just got a text that New Hanover County is going to re-visit adding back a mask mandate at a meeting in January…..insanity.
For more than just one reason. I'm disgusted by all the discarded masks laying around parking lots.
Packchem91
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My division just announced its final expectations for return to office effective Jan 10, with basically everyone being required to be in office 2-3 days per week (much to the chagrin of many folks who worked full-time remotely even pre-covid).
Not even a week later.....has been indefinitely postponed again.
Packchem91
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Oldsouljer said:

PortCityPackFan said:

Just got a text that New Hanover County is going to re-visit adding back a mask mandate at a meeting in January…..insanity.
For more than just one reason. I'm disgusted by all the discarded masks laying around parking lots.
People are nasty, aren't they.
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