Startup Plans to use CRISPR for Species De-extinction

1,002 Views | 11 Replies | Last: 2 yr ago by dogplasma
PackFansXL
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https://www.entrepreneur.com/article/384478

Colossal, a bioscience and genetics engineering company that launches today and is backed by Harvard University and some of the world's most forward-thinking scientists plans to bring back the wooly mammoth in an attempt to fight climate change.

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Fighting climate change with mammoths may seem crazy, but it has decades of research behind it including the work of George Church, Ph.D., a world-renowned pioneer in genomics. Church runs a lab at Harvard and has been exploring how to genetically re-engineer the woolly mammoth using its closest living relative, the Asian Elephant.

The reason is this: One of the greatest threats to the earth is the melting of the arctic permafrost and its massive release of the greenhouse gasses that are stored safely in its freeze. When the herds of woolly mammoth and other animals vanished, that area became covered with a forest that keeps the earth warmer. Church is betting on the idea that a resurrected population of the mammoths, if let loose in the arctic, would chomp and stomp down the bush and trees, exposing the earth to subzero temperatures and allowing the tundra's original grasslands to grow back. That ecosystem, maintained by the large creatures, would then effectively sequester carbon, rather than allowing it back into the atmosphere.

Yes, this seems crazy to me, but the idea of bringing back an extinct animal is intriguing. The possibilities for use of CRISPR technology are mindboggling. It will be interesting to see if they have any success.
WPNfamily
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Did the clowns not watch Jurassic Park?!?
wilmwolf
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WPNfamily said:

Did the clowns not watch Jurassic Park?!?


No. And a lot of scientists never watched Terminator, or pretty much any other book or film about AI, either apparently.
Just a guy on the sunshine squad.
Bell Tower Grey
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God help us all if they ever decide to work here:https://www.smithsonianmag.com/science-nature/snake-infested-island-deadliest-place-brazil-180951782/
cowboypack02
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Bell Tower Grey said:

God help us all if they ever decide to work here:https://www.smithsonianmag.com/science-nature/snake-infested-island-deadliest-place-brazil-180951782/


If there was ever a place to drop a nuke
Bell Tower Grey
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cowboypack02 said:

Bell Tower Grey said:

God help us all if they ever decide to work here:https://www.smithsonianmag.com/science-nature/snake-infested-island-deadliest-place-brazil-180951782/


If there was ever a place to drop a nuke
Damn right, brother. I despise a snake. Alive, dead, doesn't matter. They can never be killed enough to suit me.
cowboypack02
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Bell Tower Grey said:

cowboypack02 said:

Bell Tower Grey said:

God help us all if they ever decide to work here:https://www.smithsonianmag.com/science-nature/snake-infested-island-deadliest-place-brazil-180951782/


If there was ever a place to drop a nuke
Damn right, brother. I despise a snake. Alive, dead, doesn't matter. They can never be killed enough to suit me.


I'm with you. My general rule of thumb is that I stay out of the woods in the summer because that is where snakes live, but if I see one out in the open he gotta die
Packchem91
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PackFansXL said:

https://www.entrepreneur.com/article/384478

Colossal, a bioscience and genetics engineering company that launches today and is backed by Harvard University and some of the world's most forward-thinking scientists plans to bring back the wooly mammoth in an attempt to fight climate change.

Quote:

Quote:

Fighting climate change with mammoths may seem crazy, but it has decades of research behind it including the work of George Church, Ph.D., a world-renowned pioneer in genomics. Church runs a lab at Harvard and has been exploring how to genetically re-engineer the woolly mammoth using its closest living relative, the Asian Elephant.

The reason is this: One of the greatest threats to the earth is the melting of the arctic permafrost and its massive release of the greenhouse gasses that are stored safely in its freeze. When the herds of woolly mammoth and other animals vanished, that area became covered with a forest that keeps the earth warmer. Church is betting on the idea that a resurrected population of the mammoths, if let loose in the arctic, would chomp and stomp down the bush and trees, exposing the earth to subzero temperatures and allowing the tundra's original grasslands to grow back. That ecosystem, maintained by the large creatures, would then effectively sequester carbon, rather than allowing it back into the atmosphere.

Yes, this seems crazy to me, but the idea of bringing back an extinct animal is intriguing. The possibilities for use of CRISPR technology are mindboggling. It will be interesting to see if they have any success.
I saw a 60 Minutes (or some such news show) in the last year or two about Russian scientists and their efforts to import some animals - now I forget what -- into the permafrost for this very reason. An effort to recover it by essentially trampling and eating all the surroundings

IIRC though, they were talking about relocation, not regeneration.

It is interesting. And its not like I'm planning on visiting, so if a wooly mammoth steps on a few Laplanders....
Packchem91
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Bell Tower Grey said:

God help us all if they ever decide to work here:https://www.smithsonianmag.com/science-nature/snake-infested-island-deadliest-place-brazil-180951782/
Good god almighty.....imagine the poor guys who draw the short straw to have to go perform maintenance on that lighthouse. That thing looks pretty far from the shore -- imagine the trigger finger you'd have on that walk up the hill.

*It is a cool story about how the snakes evolved because their only food source was birds that would have flown away from a normal bite.
dogplasma
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dogplasma
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Unless people start driving woolly mammoths instead of Ford F-150s and Boeing 737s, I'm not sure this is the answer to climate change.
PackFansXL
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Do wooly mammoths fart? Would those gases be good or bad for the climate?
dogplasma
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Good point! Methane is worse than CO2. This could be a plot to kill us all.
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